Celastrol CAS 34157-83-0

CAS:34157-83-0

Mfumo wa Molekuli:C29H38O4

Uzito wa Masi:450.61

EINECS:636-472-5

Visawe:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(TAFADHALI PIGA SIMU); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1 (10), 3,5,7-tetraene-29-oic asidi; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

Acha Ujumbe Wako

Maelezo ya Bidhaa

Pakua

Lebo za Bidhaa

Celastrol CAS 34157-83-0 ni nini?

Celastrol haiyeyuki katika maji, mumunyifu katika dimethyl sulfoxide na ethanoli isiyo na maji. Imetokana na viambato amilifu vya kuzuia saratani katika mimea kama vile Thunder God Vine na South Snake Vine katika familia ya Celastraceae. Kizuizi bora cha proteasome, kilichothibitishwa kusababisha apoptosis ya seli ya saratani kwa kuzuia shughuli za proteasome.

Vipimo

Kipengee	Vipimo
Kiwango cha kuchemsha	645.7±55.0 °C(Iliyotabiriwa)
Msongamano	1.2
Kiwango myeyuko	219-230°C
pKa	4.78±0.70(Iliyotabiriwa)
λmax	424nm(MeOH)(lit.)
Masharti ya kuhifadhi	-20°C

Maombi

Celastrol hutumika kwa ajili ya kubainisha maudhui/kitambulisho/majaribio ya kifamasia, n.k. Athari za kifamasia: Ina sifa dhabiti za antioxidant, athari za kupambana na saratani ya angiogenesis, na athari za kupambana na baridi yabisi. Kizuizi bora cha proteasome, kilichothibitishwa kusababisha apoptosis ya seli ya saratani kwa kuzuia shughuli za proteasome.